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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS6
All Species:
26.67
Human Site:
S226
Identified Species:
58.67
UniProt:
Q7L5N1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5N1
NP_006824.2
327
36163
S226
E
H
L
I
A
Q
H
S
A
I
K
M
L
H
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100125
326
36044
S225
E
H
L
I
A
Q
H
S
A
I
K
M
L
H
S
Dog
Lupus familis
XP_536866
321
35704
S220
E
H
L
I
A
Q
H
S
A
I
K
M
L
H
S
Cat
Felis silvestris
Mouse
Mus musculus
O88545
324
35862
S223
E
H
L
I
A
Q
H
S
A
I
K
M
L
H
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NUC2
318
35518
S217
E
H
L
I
A
Q
H
S
A
I
K
M
L
H
S
Zebra Danio
Brachydanio rerio
NP_001017768
297
33615
R204
A
I
K
M
L
H
S
R
V
K
V
I
L
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCY3
341
38287
S240
E
H
L
V
A
Q
D
S
A
I
K
M
L
N
T
Honey Bee
Apis mellifera
XP_393678
338
37998
S237
E
H
L
T
A
Q
H
S
A
I
K
M
L
H
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192086
297
33638
R204
A
V
K
M
L
H
S
R
V
K
L
I
V
D
Y
Poplar Tree
Populus trichocarpa
XP_002330530
306
34249
M210
G
I
H
S
A
I
K
M
L
N
S
R
I
R
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W206
317
35640
H216
A
A
H
L
T
G
I
H
S
A
I
K
M
L
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99
97.5
N.A.
97.8
N.A.
N.A.
N.A.
N.A.
88.6
83.7
N.A.
56.8
62.7
N.A.
70
Protein Similarity:
100
N.A.
99
97.8
N.A.
98.4
N.A.
N.A.
N.A.
N.A.
93.8
87.7
N.A.
75
76.3
N.A.
80.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
100
6.6
N.A.
73.3
93.3
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
100
20
N.A.
93.3
93.3
N.A.
20
Percent
Protein Identity:
35.4
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
56.8
N.A.
N.A.
56.5
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
0
0
73
0
0
0
64
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% D
% Glu:
64
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
64
19
0
0
19
55
10
0
0
0
0
0
55
0
% H
% Ile:
0
19
0
46
0
10
10
0
0
64
10
19
10
0
0
% I
% Lys:
0
0
19
0
0
0
10
0
0
19
64
10
0
0
0
% K
% Leu:
0
0
64
10
19
0
0
0
10
0
10
0
73
10
0
% L
% Met:
0
0
0
19
0
0
0
10
0
0
0
64
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
64
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
19
0
0
0
10
0
10
0
% R
% Ser:
0
0
0
10
0
0
19
64
10
0
10
0
0
0
55
% S
% Thr:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
10
0
10
0
0
0
0
19
0
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _